2937.22.00.00 - Halogenated derivatives of adrenal cortical hormones

This HTS category, 2937.22.00.00, encompasses halogenated derivatives of adrenal cortical hormones. These are synthetic or naturally occurring compounds that mimic or modify the actions of hormones produced by the adrenal cortex. The key distinguishing feature is the presence of halogen atoms (such as fluorine, chlorine, bromine, or iodine) incorporated into the molecular structure of these steroidal hormones. These modifications often enhance the therapeutic properties or alter the metabolic fate of the parent hormone.

This classification is distinct from its siblings by its specific focus on halogen substitution. For instance, 2937.21.00.00 covers unhalogenated key adrenal cortical hormones like cortisone, hydrocortisone, prednisone, and prednisolone. Similarly, 2937.23.00.00 deals with estrogens and progestins, which are different classes of steroidal hormones with distinct physiological functions and are not primarily adrenal cortical hormones. Category 2937.29.00.00 serves as a residual category for other steroidal hormones and their derivatives not specifically enumerated elsewhere.

As a leaf node, this category does not have further subdivisions within the HTS. Classification within 2937.22.00.00 is determined by the presence of halogenation in a compound that structurally relates to adrenal cortical hormones and functions similarly. Examples might include fluorinated corticosteroids used for their anti-inflammatory properties.